Saw Palmetto

Common name

American dwarf palm tree, cabbage palm, Saw Palmetto Fruit

ID

HD0055

Scientific name of the plant

Serenoa repens, Serenoa serrulata, Sabal serrulata

Anatomical part for use

fruit

Human use

Urinary tract and genital disorders

Summary

Serenoa repens, commonly known as saw palmetto, is the sole species currently classified in the genus Serenoa. It is a small palm, growing to a maximum height around 7–10 ft (2.1–3.0 m). It is endemic to the subtropical Southeastern United States, most commonly along the south Atlantic and Gulf Coastal plains and sand hills. It grows in clumps or dense thickets in sandy coastal areas, and as undergrowth in pine woods or hardwood hammocks. (Source: Wiki)

Evidence Level

Level 4 (Individual reports repeated observed over 5 years among different countries)

Hepatotoxicity reports in literature

  • Acute liver damage due to Serenoa repens: a case report : (Source)
  • Protracted cholestatic hepatitis after the use of prostata : (Source)

Hepatotoxicity Description

Chronic therapy with saw palmetto has not been linked to serum enzyme elevations and prospective trials found little or no evidence of liver injury from its administration. However, there have been rare case reports of clinically apparent liver injury attributed to saw palmetto, although in some instances, other possible causes of liver disease were present. In the reported cases, the latency to onset was within 1 to 2 weeks of starting therapy, and clinical features resembled acute viral hepatitis with a hepatocellular pattern of serum enzyme elevations and resolution within 1 to 3 months. Immunoallergic and autoimmune features were not present. (Source: LiverTox)